An mTOuR of Epilepsy in Tuberous Sclerosis Complex
نویسندگان
چکیده
منابع مشابه
The natural history of epilepsy in tuberous sclerosis complex.
BACKGROUND Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. METHODS A retrospective chart review of all patients with TSC seen between January 2002 and October 2008. Charts were reviewed for a history of infantile spasms (IS), seizure other than IS, refractory epilepsy, Lennox-Gastaut ...
متن کاملDevelopmental outcome of epilepsy surgery in tuberous sclerosis complex.
In Tuberous sclerosis complex (TSC), neurological dysfunction, usually in association with epilepsy, is responsible for the greatest degree of disease-related disability. Epilepsy surgery is increasingly recognized as a therapeutic option given the often medication-resistant nature of the disease. Seven subjects with medically refractory epilepsy associated with TSC, who underwent surgery at a ...
متن کاملTuberous sclerosis complex: an update
Fanling Integrated Treatment Centre, 6/F, Fanling Health Centre, 2 Pik Fung Road, Fanling, New Territories Tuberous sclerosis complex (TSC), a rare autosomal dominant neurocutaneous syndrome, may be caused by mutations of either the TSC1 or TSC2 gene encoding hamartin and tuberin respectively. It is characterised by cutaneous changes, neurologic conditions and the formation of hamartomas in mul...
متن کاملCurrent management for epilepsy in tuberous sclerosis complex.
PURPOSE OF REVIEW This article reviews the most significant advances in the field of epilepsy associated with tuberous sclerosis complex, with emphasis on new advances in the knowledge of the pathophysiological mechanisms of epileptogenicity, progress in identifying the epileptogenic zone, and the rationale for surgical management in individuals with intractable seizures. RECENT FINDINGS Adva...
متن کاملSpectrum of epilepsy in tuberous sclerosis.
Tuberous sclerosis (TS) is an autosomal dominant disease that affects the brain, skin, eye, heart and kidney. The diagnostic criteria for tuberous sclerosis complex (TSC) have recently been revised. There are relatively few Indian studies on this disorder. Twenty-six patients diagnosed as having TS over a period of 18 years are being reported. The onset of seizures ranged from infancy to adoles...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2017
ISSN: 1535-7597,1535-7511
DOI: 10.5698/1535-7511.17.2.84